Blood cancers and many solid cancers have already spread to the entire body even at the time of their detection. Even when a tumor like breast cancer is detected in an apparently localised early stage, many a times, the disease comes back if surgery alone is performed for its treatment. It is assumed that even in some of the earliest tumors, some cancer cells might have spread to distant sites where they remain dormantly for an indefinite time period before eventually relapsing. That is why we need to treat the disease with medicines that can reach each and every site in our system- this forms the basis of systemic treatment for cancers.
Over the last 50 years, tremendous advances have happened in our understanding of many cancers. Many paediatric solid tumors and leukemias are now eminently curable with chemotherapy. Systemic chemotherapy has also been established as important components of treatment of cancers like testicular cancer, breast cancer, ovarian cancer and colonic cancers.
The biggest challenge about systemic chemotherapy lies in its nonselective nature. That is, the drug cannot distinguish between cancer cells and many normal rapidly dividing cells..
Most of the dreaded complications of chemotherapy like hairloss, decreased blood cell counts and life threatening infections are due to this nonselective effects on normal cells. But with recent advances in drug delivery and the introduction of the whole new gamut of more selective targeted agents, chemotherapy has evolved into a much more tolerable treatment
Autologous and allogenic bone marrow transplants have also extended the limits of modern day medical oncology in the management of blood diseases like leukemias and myeloma.
High energy X-rays are used to induce genetic damage in cancer cells, resulting in their eventual elimination by body defence mechanisms.
This forms the basis of radiotherapy, which is the most important method of nonsurgical treatment of localised cancers. Old generation Cobalt machines were effective, but resulted in significant toxicity and morbidity to the patient. Nowadays they have more or less been replaced by new generation Linear Accelerators that allow more precise treatment delivery with fewer side effects. This makes radiation a still more attractive option in patients who are not willing for; or due to medical reasons, unfit for surgery.
Other refinements that have revolutionised radiation treatment is three dimensional planning, dose painting and image guided radiotherapy have resulted in lesser toxicity and more efficacy by sparing of critical structures, and by correcting issues related to patient movement, respiration or tumor shrinkage during treatment.
Yet another advancement is in the field of brachytherapy where radioactive materials may be placed within the tumor to deliver continuous radiation with least amount of side effects to normal tissues. Precision techniques and image guidance has also allowed the focussed use of radiation beams as gamma knife to treat tumors within critical and surgically inaccessible locations.
Traditionally, surgery had been regarded as one of the most important weapons in the fight against cancer, and its status is still unchanged. But rather than trying to remove more and more to push for a possible cure, conserving functioning tissue without compromising cure has become the key to successful cancer surgery.
The power of conservatism has slowly spread across the fields of surgery in breast cancer, bone and soft tissue cancer, cancer of the kidney and urinary bladder, laryngeal cancer and rectal cancer now. Surgical steps have become more or less standardised, and due care is exercised to harvest enough number of lymph nodes to ensure oncological adequacy. The evolution of surgeons who exclusively perform cancer surgeries is a step towards the right direction, so is the recognition that results of treatment and better with high volume centres. Rightly done surgery is now recognised as an important prognostic factor in many cancers. The surgeon’s role has become even more critical as an active member of multidisciplinary team in present day cancer management. `
One in eight women will be diagnosed with breast cancer during her lifetime. It accounts for more than 30 percent of all cancers found in women. Breast cancer is not selective. The majority of women diagnosed with breast cancer have no family history of the disease and while it occurs more often in women who are over the age of 50, younger women are at risk too. KCC Breast Cancer Center is solely dedicated to the prevention, early diagnosis and treatment of the cancer.
Our Breast Cancer Center will provide screening for early diagnosis using the mammogram and ultrasound and will conduct programmes for both medical personnel as well as public awareness.Â The Gynecological Oncology will focus on pap smears for prevention and early diagnosis of cervical cancer as well as combined modality approach for the treatment of cancer in the cervix, uterus and ovary.
- Gynecologic oncology is a specialized field of medicine that focuses on cancers of the female reproductive System.
- KCC Offers the diagnosis and treatment of Ovarian cancer, uterine cancer,Vaginal cancer,Cervical cancer, Vulvar cancer etc.